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Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S4246 Tranylcypromine HCl Tranylcypromine HCl is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.
Sci Bull (Beijing), 2024, S2095-9273(24)00799-0
Cell Rep, 2023, 42(6):112566
Biomolecules, 2023, 13(3)521
Verified customer review of Tranylcypromine HCl
S9464 Tranylcypromine Sulfate Tranylcypromine Sulfate is an irreversible inhibitor of monoamine oxidase (MAO) with a rapid onset of activity.
PLOS One, January 3, 2023, e0279063
Cell Communication and Signaling, January 15, 2026, Online ahead of print
International Journal of Molecular Sciences, 2022, 4213
S3212 Moclobemide (Ro 111163) Moclobemide (Ro 111163) is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.
J Gerontol A Biol Sci Med Sci, 2022, 77-8:1485-1493
The Journals of Gerontology: Series A, 2022, 1485-1493
Biology of Reproduction, 2021, 1486-1497
Verified customer review of Moclobemide (Ro 111163)
S3690 Pargyline hydrochloride Pargyline is an irreversible inhibitor of monoamine oxidase (MAO)-B with Ki values of 13 and 0.5 μM for time-dependent inhibition of the activity of MAO-A and -B, respectivey.
J Immunother Cancer, 2024, 12(11)e009805
Genome Medicine, 2021, 168
Genome Med, 2021, 13(1):168
S2102 Rasagiline Mesylate Rasagiline Mesylate (TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate) is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.
J Immunother Cancer, 2024, 12(11)e009805
Front Pharmacol, 2022, 13:1004215
EMBO Mol Med, 2021, e13929
S5795 Rasagiline Rasagiline (TVP-1012) is a novel selective and irreversible MAO-B propargylamine inhibitor with in vitro IC50s of 4.43 nM and 412 nM for MAO-B and MAO-A, respectively.
Journal of Biosciences and Medicines, 2024, 32-44
Frontiers in Pharmacology, 2022, 1004215
EMBO Molecular Medicine, 2021, e13929
S5269 J147 J147, a curcumin derivative, is a potent neurogenic and neuroprotective compound developed for the treatment of neurodegenerative conditions associated with aging.
J Mol Histol, 2023, 54(6):725-738.
Journal of Molecular Histology, 2023, 725-738
Frontiers in Neurology, 2022, 821082
S4033 Sennoside A Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
Sci Adv, 2022, 8(15):eabm3471
Front Pharmacol, 2020, 11:566099
S2339 Paeonol Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM.
International Journal of Biological Sciences, September 07 2019, 2497-2508
Biochem Biophys Res Commun, 2023, 656:86-96
International Journal of Biological Sciences, 2019, 2497-2508
S4717 Isatin Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor with an IC50 of 15 μM and more active against MAO-B than MAO-A.
Adv Sci (Weinh), 2025, 12(28):e2417318
Cell Rep, 2022, 38(13):110559

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