Active Pharmaceutical Ingredients

Catalog No. Product Name Information
S3058 Danofloxacin Mesylate Danofloxacin (CP-76136-27) is a fluoroquinolone antibacterial for veterinary use, with MIC90 of 0.28 μM.
S4099 Dexlansoprazole Dexlansoprazole (T 168390, TAK 390,(R)-Lansoprazole), the dextrorotatory enantiomer of lansoprazole, is a proton pump inhibitor (PPI) formulated to have dual delayed-release properties. Dexlansoprazole selectively suppresses gastric acid secretion by direct inhibition of the H(+),K(+)-ATPase proton pump in the gastric parietal cell.
S1465 Moxifloxacin (BAY12-8039) HCl Moxifloxacin (Avelox, Avalox,BAY12-8039 HCl) is a fourth-generation synthetic fluoroquinolone antibacterial agent.
S1904 Avobenzone Avobenzone (Butyl methoxydibenzoylmethane, BF2AVB) is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.
S2544 Cefprozil hydrate Cefprozil hydrate is a semi-synthetic broad-spectrum cephalosporin antibiotic, used to treat certain infections caused by bacteria, such as bronchitis and infections of the ears, throat, sinuses, and skin.
S2585 Brompheniramine hydrogen maleate Brompheniramine hydrogen maleate(Brompheniramine maleate) is a histamine H1 receptors antagonist.
S4100 Esmolol HCl Esmolol (ASL8052) is a cardioselective b-blocker, used to control rapid heartbeats or abnormal heart rhythms.
S4212 Tenatoprazole Tenatoprazole (TU-199,STU-Na) is a prodrug of the proton pump inhibitor (PPI) class, which inhibits proton transport with IC50 of 3.2 μM. Tenatoprazole labels only the gastric H(+),K(+)-ATPase alpha-subunit, approximately 2.6 nM/mg of tenatoprazole is bound to the H(+),K(+)-ATPase.
S2588 Calcium Folinate Calcium Folinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.Solutions are unstable and should be fresh-prepared.
S3031 Linagliptin (GSK2118436) Linagliptin (GSK2118436) is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM and exhibits a 10,000-fold higher selectivity for DPP-4 than for other dipeptidyl peptidases such as DPP-2, DPP-8, and DPP-9. Linagliptin activates glomerular autophagy in a model of type 2 diabetes. DPP4 mediates ferroptosis in TP53-deficient CRC cells.
S4213 Dirithromycin Dirithromycin (LY-237216, ASE 136,Dynabac) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.
S1168 Valproic Acid sodium Valproic Acid sodium is a HDAC inhibitor by selectively inducing proteasomal degradation of HDAC2, used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. Valproic acid induces Notch1 signaling in small cell lung cancer (SCLC) cells. Valproic acid is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α.
S1469 Calcifediol Calcifediol (Calcidiol, Didrogyl, Hidroferol, 25-hydroxyvitamin D3, 25-Hydroxycholecalciferol) is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM).
S2170 Givinostat (ITF2357) Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM in cell-free assays. Phase 2.
S1831 Carvedilol Carvedilol (BM-14190, SKF 105517) is a non-selective beta blocker/alpha-1 blocker, used to treat congestive heart failure (CHF) and high blood pressure.
S4214 Sucralose Sucralose (E955,Trichloro Sucrose) is an artificial and noncaloric sweetener, not broken down by the body.
S1468 Alfacalcidol Alfacalcidol (1-hydroxycholecalciferol) is a non-selective VDR activator medication.
S1823 Fenoprofen Calcium Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.
S4215 Ribostamycin Sulfate Ribostamycin Sulfate(Vistamycin Sulfate,Landamycine) is an aminoglycoside antibiotic, containing a neutral sugar moiety, and is produced by Streptomyces ribosidificus.
S1467 Doxercalciferol Doxercalciferol (1α-hydroxyvitamin D2) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.