HomeActive Pharmaceutical Ingredients

Active Pharmaceutical Ingredients

Catalog No. Product Name Information
S1730 Indapamide Indapamide is a non-thiazide sulphonamide diuretic compound, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
S2497 Pancuronium dibromide Pancuronium dibromide is a competitive nicotinic acetylcholine receptor antagonist, used as a muscle relaxant.
S1876 Valaciclovir HCl Valaciclovir HCl, an aciclovir prodrug, inhibits activity of virus DNA polymerase, used to treat infections caused by herpes simplex virus (HSV) and varicella zoster virus, and for prophylaxis against cytomegalovirus (CMV).
S1610 Metolazone Metolazone (SR 720-22) is a diuretic that primarily used to treat congestive heart failure and high blood pressure.
S1959 Tolfenamic Acid Tolfenamic Acid(Clotam) is a COX-2 inhibitor with IC50 of 0.2 μM.
S3047 Otilonium Bromide Otilonium bromide is an antimuscarinic.
S4019 Avanafil Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, >121-fold selectivity over other PDEs.
S2606 Mifepristone Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.
S1732 Mitotane Mitotane (NCI-C04933), is an antineoplastic medication used in the treatment of adrenocortical carcinoma.
S2499 Phenoxybenzamine HCl Phenoxybenzamine HCl (NSC 37448, NCI-c01661) is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.
S1837 Flubendazole Flubendazole (Flumoxanal, NSC 313680) is an autophagy inducer by targeting Atg4B, used to treat internal parasite and worm infection.
S3050 Palonosetron HCl Palonosetron HCl (RS 25259, RS 25259 197) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
S4020 Sodium Picosulfate Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.
S1033 Nilotinib Nilotinib is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.
S1324 Doxazosin Mesylate Doxazosin, a quinazoline-derivative, selectively antagonizes postsynaptic α1-adrenergic receptors, used in the treatment of high blood pressure and urinary retention associated with benign prostatic hyperplasia.
S2500 Propafenone HCl Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.
S2040 Nimesulide Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.
S3048 Solifenacin succinate Solifenacin succinate (YM905) is a urinary antispasmodic of the antimuscarinic class.
S2693 Resminostat Resminostat (RAS2410) dose-dependently and selectively inhibits HDAC1/3/6 with IC50 of 42.5 nM/50.1 nM/71.8 nM, less potent to HDAC8 with IC50 of 877 nM.
S1326 Edaravone Edaravone (MCI-186) is a novel potent free radical scavenger that has been clinically used to reduce the neuronal damage following ischemic stroke.