HomeActive Pharmaceutical Ingredients

Active Pharmaceutical Ingredients

Catalog No. Product Name Information
S2221 Apatinib (YN968D1) mesylate Apatinib mesylate (YN968D1, Rivoceranib) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib mesylate induces both autophagy and apoptosis.
S4202 Verapamil HCl Verapamil HCl is an L-type calcium channel blocker that is a class IV anti-arrhythmia agent. Verapamil inhibits both permeability-glycoprotein (P-gp) and CYP3A4.
S4105 Closantel Sodium Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S4106 Closantel Closantel (R-31520,nsc 335306) is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.
S1188 Anastrozole Anastrozole is a third-generation nonsteroidal selective aromatase inhibitor. It may offer greater selectivity compared with other aromatase inhibitors, being without any intrinsic endocrine effects and with no apparent effect on the synthesis of adrenal steroids.
S1223 Epirubicin HCl Epirubicin HCl, a semisynthetic L-arabino derivative of doxorubicin, is an antineoplastic agent by inhibiting Topoisomerase. Epirubicin induces apoptosis.
S3147 Entacapone Entacapone (OR-611) inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM. Entacapone can be used for the research of Parkinson's disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders.
S4390 Brucine Brucine((-)-Brucine), an alkaloid closely related to strychnine, is most commonly found in the Strychnos nux-vomica tree.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
S6421 Diroximel Fumarate Diroximel Fumarate (ALKS-8700) is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body.
S5398 Nefazodone hydrochloride Nefazodone hydrochloride (BMY-13754-1) is the hydrochloride salt form of nefazodone, which is an atypical antidepressant showing antagonistic activity on serotonin reuptake.
S5944 Butenafine Butenafine is a synthetic benzylamine antifungal agent.
S5939 Bendamustine Bendamustine is a nitrogen mustard drug used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin's lymphoma.
S5938 Benazepril Benazepril is used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor.
S6307 2-Methyllactic acid 2-Methyllactic acid (2-Hydroxyisobutyric acid, Acetonic acid) is a metabolite of methyl tertiary-butyl ether.
S6326 D-3-Phenyllactic acid D-3-Phenyllactic acid is a chiral building block that is used in preparation of statine.
S6406 Ferrous fumarate Ferrous fumarate (Iron(II)) is the fumarate salt form of the mineral iron and is used in treatment of iron deficiency anemia.
S1210 Methotrexate Methotrexate, analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells. It forms an inactive ternary complex with DHFR and NADPH. Methotrexate (MTX) induces apoptosis.
S6140 16-Dehydroprogesterone 16-Dehydroprogesterone is a chemical derived from a progesterone.
S4126 Retinyl (Vitamin A) Palmitate Retinyl (Vitamin A) Palmitate is a more stable, synthetic version of the essential nutrient vitamin A joined to palmitic acid.
S1999 Sodium butyrate Sodium butyrate (NaB, Butanoic acid sodium salt), sodium salt of butyric acid, is a histone deacetylase inhibitor and competitively binds to the zinc sites of class I and II histone deacetylases (HDACs). Sodium butyrate (NaB) inhibits cell cycle progression, promotes differentiation, and induces apoptosis and autophagy in several types of cancer cells.