Home Biosimilar Antibodies Others ADC null -HER2 inhibitor Trastuzumab deruxtecan (DS-8201a, T-DXd) For research use only.
Not for use in humans.

Trastuzumab deruxtecan (DS-8201a, T-DXd)

Synonyms: DS-8201

Trastuzumab deruxtecan (DS-8201a, T-DXd) is an antibody-drug conjugate (ADC) composed of an anti-HER2 (human epidermal growth factor receptor 2) antibody and a cytotoxic topoisomerase I inhibitor. Trastuzumab deruxtecan shows durable antitumor activity. Trastuzumab deruxtecan has a molecular weight of 153KDa.

Trastuzumab deruxtecan (DS-8201a, T-DXd)

CAS No. 1826843-81-5

Purity & Quality Control

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Trastuzumab deruxtecan (DS-8201a, T-DXd) is an antibody-drug conjugate (ADC) composed of an anti-HER2 (human epidermal growth factor receptor 2) antibody and a cytotoxic topoisomerase I inhibitor. Trastuzumab deruxtecan shows durable antitumor activity. Trastuzumab deruxtecan has a molecular weight of 153KDa.

Product Details

CAS No. 1826843-81-5
Molecular Weight 153000
DAR 7.8
ADC antiody Trastuzumab
ADC cytotoxin DXd
Formulation 100 mM Pro-Ac, 20 mM Arg, pH 5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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