Home Neuronal Signaling 5-HT Receptor antagonist Cyclobenzaprine HCl For research use only.

Cyclobenzaprine HCl

Synonyms: Cyclobenzaprine hydrochloride

Cyclobenzaprine HCl(Cyclobenzaprine hydrochloride) is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.

Cyclobenzaprine HCl Chemical Structure

Cyclobenzaprine HCl Chemical Structure

CAS No. 6202-23-9

Purity & Quality Control

Cyclobenzaprine HCl Related Products

Signaling Pathway

5-HT Receptor Signaling Pathways

5-HT Receptor Signaling Pathway

Biological Activity

Description Cyclobenzaprine HCl(Cyclobenzaprine hydrochloride) is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.
Targets
5-HT2 receptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03700970 Completed
Breast Reconstruction|Anesthesia|Transverse Abdominis Plane Block
Vanderbilt University Medical Center
 June 13 2019 Phase 4
NCT03443960 Completed
Healthy Subjects
Tonix Pharmaceuticals Inc.
 January 29 2018 Phase 1
NCT03168022 Completed
Healthy Adults
Tonix Pharmaceuticals Inc.
 December 16 2015 Phase 1
NCT01921296 Terminated
Sleep Initiation and Maintenance Disorders|Pain
Lynn Henry|Damon Runyon Cancer Research Foundation|University of Michigan Rogel Cancer Center
 August 2013 Phase 2

Chemical Information & Solubility

Molecular Weight 311.85 Formula

C20H22ClN
CAS No. 6202-23-9 SDF Download Cyclobenzaprine HCl SDF
Smiles CN(C)CCC=C1C2=CC=CC=C2C=CC3=CC=CC=C31.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 62 mg/mL ( (198.81 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 62 mg/mL

Ethanol : 62 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

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