Home Biosimilar Antibodies Angiogenesis HER2 null -Microtubule Associated inhibitor Trastuzumab Emtansine（T-DM1） For research use only.
Not for use in humans.

Trastuzumab Emtansine（T-DM1）

Synonyms: Ado-Trastuzumab emtansine

Trastuzumab Emtansine(T-DM1,Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1.Trastuzumab emtansine has a molecular weight of 145kDa.This product is supplied as 10mg/ml PBS solution.

Trastuzumab Emtansine（T-DM1）

CAS No. 1018448-65-1

Purity & Quality Control

Batch: D400301 Purity: 99.59% Protein concentration: 10mg/ml Endotoxin Level: ＜1EU/mg
99.59

Choose Selective HER2 Inhibitors

Name Citation HER2 Others
Canertinib (CI-1033) 46 EGFR
CP-724714 108
Sapitinib (AZD8931) 46 ErbB3,EGFR
CUDC-101 22 EGFR,HDAC,HDAC1
Mubritinib (TAK 165) 38
AEE788 (NVP-AEE788) 13 EGFR,c-Abl,FLT1
AC480 (BMS-599626) 10 HER1,HER4
TAK-285 4 EGFR/HER1,HER4,MEK1
Tyrphostin AG 879 3 Trk
Poziotinib 33 HER1,HER4
HER2-Inhibitor-1
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Trastuzumab Emtansine(T-DM1,Ado-Trastuzumab emtansine) is an antibody-drug conjugate (ADC) that incorporates the HER2-targeted antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent DM1.Trastuzumab emtansine has a molecular weight of 145kDa.This product is supplied as 10mg/ml PBS solution.

Product Details

CAS No. 1018448-65-1
Molecular Weight 145000
DAR 3.6
ADC antiody Trastuzumab
ADC cytotoxin DM1
Formulation 10mg/mL in PBS
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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