Serplulimab (Anti-PDCD1 / PD-1 / CD279)

Synonyms: HLX 10

Catalog No.A2381 Purity:≥99%

Serplulimab (Anti-PDCD1 / PD-1 / CD279) is a humanized monoclonal antibody directed against the negative immunoregulatory human cell receptor programmed cell death protein 1 (PD-1; PDCD1; CD279), with potential immune checkpoint inhibitory and antineoplastic activities. MW: 145.5 kD.

Purity & Quality Control

≥99

Choose Selective PD-1/PD-L1 Inhibitors

Name	Citation	PD-1/PD-L1 interaction	PD-1	PD-1/PD-L1
GS-4224	0	++++		++++
INCB086550	0	++		++
BMS-1001	0	+		+
BMS-1166	5	+++
PD-1/PD-L1 Inhibitor 3	12	+++
BMS-1	12	++
BMS202	21	+
CA-170 (AUPM-170)			✔
SR 0987		✔		IL17,RORγt
Spartalizumab (anti-PD-1)		✔
Camrelizumab (anti-PD-1)		✔
AUNP-12			✔

Expand to Check More

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Serplulimab (Anti-PDCD1 / PD-1 / CD279) is a humanized monoclonal antibody directed against the negative immunoregulatory human cell receptor programmed cell death protein 1 (PD-1; PDCD1; CD279), with potential immune checkpoint inhibitory and antineoplastic activities. MW: 145.5 kD.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2231029-82-4
Molecular Weight	145.5 kDa
Isotype	Human IgG4SP
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

If you have any other enquiries, please leave a message.

* Indicates a Required Field

* Name Please enter your name.

* Email Please enter your email. Please enter a valid email address.

Phone

* Comments: Please write something to us.

Tags: buy Serplulimab (Anti-PDCD1 / PD-1 / CD279) | Serplulimab (Anti-PDCD1 / PD-1 / CD279) supplier | purchase Serplulimab (Anti-PDCD1 / PD-1 / CD279) | Serplulimab (Anti-PDCD1 / PD-1 / CD279) cost | Serplulimab (Anti-PDCD1 / PD-1 / CD279) manufacturer | order Serplulimab (Anti-PDCD1 / PD-1 / CD279) | Serplulimab (Anti-PDCD1 / PD-1 / CD279) distributor