Home Biosimilar Antibodies Immunology & Inflammation PD-1/PD-L1 inhibitor Reozalimab(Ibi318) (Anti-PD-1 & PD-L1) For research use only.
Not for use in humans.

Reozalimab(Ibi318) (Anti-PD-1 & PD-L1)

Synonyms: LY3434172, Anti-PD-1/Anti-PD-L1 Bispecific Antibody IBI318

Reozalimab(Ibi318) is a first-in-class recombinant IgG1 bispecific antibody that targets both PD-1 and PD-L1, with checkpoint inhibitory, immunostimulating, and antineoplastic activities. It fully blocks the PD-1 pathway, disrupts PD-L1/CD80 interactions, and enhances T cell activation for improved tumor cell killing. M.W 143.84 kDa

Reozalimab(Ibi318) (Anti-PD-1 & PD-L1)

Choose Selective PD-1/PD-L1 Inhibitors

Name Citation PD-1/PD-L1 interaction PD-1 PD-L1 PD-1/PD-L1 Others
GS-4224 0
INCB086550 1
BMS-1001 0
BMS-1166 5
PD-1/PD-L1 Inhibitor 3 12
BMS-1 12
BMS202 22
CA-170 (AUPM-170)
SR 0987 IL17,RORγt
Spartalizumab (anti-PD-1)
Camrelizumab (anti-PD-1)
AUNP-12
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Reozalimab(Ibi318) is a first-in-class recombinant IgG1 bispecific antibody that targets both PD-1 and PD-L1, with checkpoint inhibitory, immunostimulating, and antineoplastic activities. It fully blocks the PD-1 pathway, disrupts PD-L1/CD80 interactions, and enhances T cell activation for improved tumor cell killing. M.W 143.84 kDa

Product Details

CAS No. 2445259-99-2
Source CHO
Storage
(From the date of receipt)		 -80℃

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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