QS11

Name: QS11
Brand: Selleck Chemicals
SKU: E4716
Rating: 5 (1 reviews)

Catalog No.E4716 Purity:97.65%

QS11 acts as an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 μM. QS11 regulates Wnt/β-catenin signaling by interacting with ARF GTPase-activating protein 1 (ARFGAP1) and influences protein trafficking. Additionally, QS11 suppresses the migration of breast cancer cells that overexpress ARFGAP1.

QS11 Chemical Structure

CAS No. 944328-88-5

Purity & Quality Control

Batch: E471601 DMSO]100 mg/mL]false]Ethanol]25 mg/mL]false]Water]Insoluble]false Purity: 97.65%

97.65

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Biological Activity

Description

Targets

ARFGAP1 ^[1]

1.5 μM(EC50)

References

[1] Zhang Q, et al. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7444-8.

Chemical Information & Solubility

Molecular Weight	567.69	Formula
CAS No.	944328-88-5	SDF	Download QS11 SDF
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( (176.15 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 25 mg/mL

Water : Insoluble

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In vivo
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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