Home Transmembrane Transporters Sodium Channel inhibitor - DNA Methyltransferase inhibitor Procainamide HCl For research use only.

Procainamide HCl

Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias.

Procainamide HCl Chemical Structure

Procainamide HCl Chemical Structure

CAS No. 614-39-1

Purity & Quality Control

Batch: S429401 DMSO]54 mg/mL]false]Water]54 mg/mL]false]Ethanol]54 mg/mL]false Purity: 99.09%
99.09

Procainamide HCl Related Products

Signaling Pathway

Sodium Channel Signaling Pathways

Sodium Channel Signaling Pathway

Biological Activity

Description Procainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor, used in the treatment of cardiac arrhythmias.
Targets
DNA methyltransferase [1] Sodium channel [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01205529 Completed
Atrial Fibrillation
Vanderbilt University Medical Center|National Heart Lung and Blood Institute (NHLBI)
 November 2010 Not Applicable

Chemical Information & Solubility

Molecular Weight 271.79 Formula

C13H22ClN3O
CAS No. 614-39-1 SDF Download Procainamide HCl SDF
Smiles CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 54 mg/mL ( (198.68 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 54 mg/mL

Ethanol : 54 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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