PVP (Polyvinylpyrrolidone)

Synonyms: Polyvidone, Povidone

PVP (Polyvinylpyrrolidone) is an inert, water-soluble, non-toxic, temperature-resistant, pH-stable, biocompatible, biodegradable polymer that helps to encapsulate and cater both hydrophilic and lipophilic drugs. Polyvinylpyrrolidone has been widely tested and used as an effective wound healing accelerator.

PVP (Polyvinylpyrrolidone) Chemical Structure

PVP (Polyvinylpyrrolidone) Chemical Structure

CAS No. 9003-39-8

Purity & Quality Control

Batch: S359601 DMSO]100 mg/mL]false]Water]100 mg/mL]false]Ethanol]100 mg/mL]false Purity: 98.15%
98.15

PVP (Polyvinylpyrrolidone) Related Products

Biological Activity

Description PVP (Polyvinylpyrrolidone) is an inert, water-soluble, non-toxic, temperature-resistant, pH-stable, biocompatible, biodegradable polymer that helps to encapsulate and cater both hydrophilic and lipophilic drugs. Polyvinylpyrrolidone has been widely tested and used as an effective wound healing accelerator.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05745467 Withdrawn
SARS-CoV-2 Acute Respiratory Disease
University of Iowa|3M
July 3 2024 Phase 4
NCT06379243 Recruiting
Osteoporosis Fracture|Osteoporosis Vertebral|Compression Fracture|Perform PVP / PKP Treatment
The Seventh Affiliated Hospital of Sun Yat-sen University|The Fourth Affiliated Hospital of Guangzhou Medical University|Huizhou Municipal Central Hospital|Dongguan Hospital of Traditional Chinese Medicine
December 1 2023 Not Applicable
NCT05696132 Not yet recruiting
MRSA
Nantes University Hospital
February 2023 Phase 2
NCT05587179 Completed
Unconsciousness
Centre for Evidence-Based Practice Belgium|University Hospital Antwerp
December 21 2022 Not Applicable

Chemical Information & Solubility

Molecular Weight Formula

(C6H9NO)n

CAS No. 9003-39-8 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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