Home Neuronal Signaling Serotonin Transporter inhibitor Paroxetine mesylate For research use only.

Paroxetine mesylate

Synonyms: BRL-29060A mesylate,FG-7051 mesylate

Paroxetine Mesylate(BRL-29060A mesylate,FG-7051 mesylate) is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.

Paroxetine mesylate Chemical Structure

Paroxetine mesylate Chemical Structure

CAS No. 217797-14-3

Purity & Quality Control

Batch: S523901 DMSO]85 mg/mL]false]Water]10 mg/mL]false]]]false Purity: 98%
98

Paroxetine mesylate Related Products

Biological Activity

Description Paroxetine Mesylate(BRL-29060A mesylate,FG-7051 mesylate) is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01829919 Completed
Postmenopausal Symptoms
Noven Therapeutics
 July 2011 Phase 1
NCT01361308 Completed
Postmenopausal Symptoms
Noven Therapeutics
 May 2011 Phase 3
NCT01101841 Completed
Hot Flashes
Noven Therapeutics
 March 2010 Phase 3
NCT00786188 Completed
Hot Flashes
Noven Therapeutics
 November 2008 Phase 2

Chemical Information & Solubility

Molecular Weight 425.47 Formula

C19H20FNO3.CH4O3S
CAS No. 217797-14-3 SDF --
Smiles CS(=O)(=O)O.C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 85 mg/mL ( (199.77 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 10 mg/mL


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In vivo
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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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