Olinvacimab (Anti-VEGFR2 / KDR / CD309)

Synonyms: TTAC-0001

Catalog No.A2979 Purity:99%

Olinvacimab (Anti-VEGFR2 / KDR / CD309) is a fully human monoclonal antibody targeting VEGFR2. It has antiangiogenic activity and can be used for the research of recurrent glioblastoma and breast cancer. MW :146.88 KD

Purity & Quality Control

Batch: A297901 Purity: 99% Protein concentration: 6.057mg/ml Endotoxin Level: ＜1EU/mg

Choose Selective VEGFR Inhibitors

Name	Citation	VEGFR1	VEGFR2	VEGFR3	VEGFR	VEGF	Others
Foretinib	93	+++	++++	++++			Met,Tie-2,RON
Cediranib (AZD2171)	67	+++	++++	++++			c-Kit,PDGFRβ,FGFR1
PD173074	120		+				FGFR1
Dovitinib (TKI-258)	50	+++	++	+++			FLT3,c-Kit,FGFR1
Linifanib (ABT-869)	32	++++	++++	+			CSF-1R,FLT3,Kit
Vatalanib (PTK787) 2HCl	52	+	+	+			PDGFRβ,c-Kit,c-Fms
RAF265 (CHIR-265)	23		++				B-Raf
Motesanib Diphosphate (AMG-706)	12	++++	++++	+++			Kit,RET,PDGFR
Brivanib (BMS-540215)	9	+	++				FGFR1
MGCD-265 analog	12	++++	++++	++++			Met,RON,Tie-2
AEE788 (NVP-AEE788)	13	+	+				EGFR,HER2/ErbB2,c-Abl
ENMD-2076	8		+	++			FLT3,RET,Aurora A
OSI-930	7	+++	+++				CSF-1R,LCK,C-Raf
CYC116	10		+				Aurora A,Aurora B,FLT3
Ki8751	20		++++				c-Kit,PDGFRα
Telatinib	5		+++	++++			c-Kit,PDGFRα
PP121	5		+++				PDGFR,Hck,mTOR
KRN 633	6	+	+	+			PDGFRα,c-Kit,BTK
SAR131675	30			++
Apatinib (YN968D1) mesylate	23		++++				RET
BMS-794833	1		++				Met
Brivanib Alaninate (BMS-582664)	2	+	++				FGFR1
Golvatinib (E7050)	8		++				c-Met
Semaxanib (SU5416)	19		+
ZM 323881 HCl	18		++++
ZM 306416	13	+					Src,Abl
R1530	0		+++				FGFR1
Chiauranib	0		+++				c-Kit,CSF-1R,Aurora B
Emvododstat (PTC299)	0					++++	Dihydroorotate dehydrogenase
XL092	0		++++				AXL,MER,MET
Lucitanib (E3810) hydrochloride	1	+++	++	+++			FGFR1,FGFR2
Ningetinib	0		++++				Axl,c-Met
Ki20227	1		+++				c-Fms,PDGFRβ,c-Kit
Tyrphostin AG1433	0		+				PDGFRβ
SU14813	2	++++	+				PDGFRβ,KIT
Sulfatinib	1	++++	++	++++			CSF1R,FGFR1
CS-2660 (JNJ-38158471)	0		+				RET,Kit
SU5204	1		+				HER2
SU5214	0		+				EGFR
SU5205	0		+
SU5408	2		+
Pamufetinib (TAS-115)	0		++				recombinant MET
ODM-203	0	++	+++	+++			FGFR3,FGFR1,FGFR2
WHI-P180	0		+				RET
Altiratinib	2		+++				MET Y1230C,TrkA,TrkC
Motesanib (AMG-706)	11	++++	++++	+++			c-Kit,c-Ret,PDGFR
Fruquintinib	4	++	++	++++
Apatinib	26		++++				RET
Cediranib Maleate	14	+++	++++	++++			c-Kit,PDGFRβ,FGFR1
Toceranib phosphate	1		+++				PDGFR
Anlotinib (AL3818) dihydrochloride	36		++++	++++			c-Kit
Sitravatinib (MGCD516)	4	+++	+++	++++			DDR2,EPHA3,Axl
BFH772	0		++++
BAW2881 (NVP-BAW2881)	2	+	+++	+			C-Raf-1,B-RAFV599E,c-Abl
SU5402	17		++				FGFR1,PDGFRβ
Dovitinib (TKI258) Lactate monohydrate	31	+++	++	+++			FLT3,c-Kit,FGFR1
LY2874455	14		+++				FGFR2,FGFR1,FGFR4
SKLB1002	4		++
AZD2932	3		+++				PDGFRβ,Flt3,c-Kit
WAY-340935		✔
hVEGF-IN-1					✔
4SC-203				✔
Chebulinic acid				✔
Nastorazepide				✔
Vorolanib				✔		PDGFR
MAZ51			✔			RhoA,GSK3β,Akt
SU5208		✔
SU5614		✔				FLT3,c-Kit,RET
AG-13958				✔
SKLB 610		✔				FGFR2,PDGFR
SU1498		✔
ZD-4190		✔				Flt-1
PDGFR inhibitor 1		✔				PDGFR,Kit,c-Fms
Taxifolin (Dihydroquercetin)		✔

Expand to Check More

1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description	Olinvacimab (Anti-VEGFR2 / KDR / CD309) is a fully human monoclonal antibody targeting VEGFR2. It has antiangiogenic activity and can be used for the research of recurrent glioblastoma and breast cancer. MW :146.88 KD

References
[1] Lee WS, et al. MAbs. 2015;7(5):957-68.

References

[1] Lee WS, et al. MAbs. 2015;7(5):957-68.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2095504-49-5
Molecular Weight	146.88
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

If you have any other enquiries, please leave a message.

* Indicates a Required Field

* Name Please enter your name.

* Email Please enter your email. Please enter a valid email address.

Phone

* Comments: Please write something to us.

Tags: buy Olinvacimab (Anti-VEGFR2 / KDR / CD309) | Olinvacimab (Anti-VEGFR2 / KDR / CD309) supplier | purchase Olinvacimab (Anti-VEGFR2 / KDR / CD309) | Olinvacimab (Anti-VEGFR2 / KDR / CD309) cost | Olinvacimab (Anti-VEGFR2 / KDR / CD309) manufacturer | order Olinvacimab (Anti-VEGFR2 / KDR / CD309) | Olinvacimab (Anti-VEGFR2 / KDR / CD309) distributor