Home Neuronal Signaling Opioid Receptor antagonist Naloxegol Oxalate For research use only.

Naloxegol Oxalate

Synonyms: NKTR-118 oxalate

Naloxegol oxalate (NKTR-118 oxalate) is a μ-opioid-receptor antagonist with a Ki of 33.8 nM. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation.

Naloxegol Oxalate Chemical Structure

Naloxegol Oxalate Chemical Structure

CAS No. 1354744-91-4

Purity & Quality Control

Batch: E286801 DMSO]100 mg/mL]false]Water]100 mg/mL]false]Ethanol]100 mg/mL]false Purity: 99.52%
99.52

Naloxegol Oxalate Related Products

Signaling Pathway

Opioid Receptor Signaling Pathways

Opioid Receptor Signaling Pathway

Biological Activity

Description Naloxegol oxalate (NKTR-118 oxalate) is a μ-opioid-receptor antagonist with a Ki of 33.8 nM. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation.
Targets
Opioid receptor [1]
33.8 nM(Ki)

Chemical Information & Solubility

Molecular Weight 741.82 Formula

C34H53NO11.C2H2O4
CAS No. 1354744-91-4 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (134.8 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL


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