Home Metabolism PDE inhibitor Mirodenafil Dihydrochloride For research use only.

Mirodenafil Dihydrochloride

Synonyms: SK-3530 dihydrochloride

Mirodenafil Dihydrochloride(SK-3530 dihydrochloride) is an oral phosphodiesterase type 5 (PDE-5) inhibitor used to treat erectile dysfunction (ED).

Mirodenafil Dihydrochloride Chemical Structure

Mirodenafil Dihydrochloride Chemical Structure

CAS No. 862189-96-6

Purity & Quality Control

Batch: S589401 DMSO]100 mg/mL]false]Ethanol]13 mg/mL]false]Water]1 mg/mL]false Purity: 99.93%
99.93

Mirodenafil Dihydrochloride Related Products

Signaling Pathway

PDE Signaling Pathways

PDE Signaling Pathway

Biological Activity

Description Mirodenafil Dihydrochloride(SK-3530 dihydrochloride) is an oral phosphodiesterase type 5 (PDE-5) inhibitor used to treat erectile dysfunction (ED).
Targets
PDE-5 [1]

Chemical Information & Solubility

Molecular Weight 604.59 Formula

C26H37N5O5S.2ClH
CAS No. 862189-96-6 SDF --
Smiles Cl.Cl.CCCOC1=C(C=C(C=C1)[S;v6](=O)(=O)N2CCN(CCO)CC2)C3=NC(=O)C4=C(N3)C(=C[N]4CC)CCC
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (165.4 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 13 mg/mL

Water : 1 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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