Methotrexate metabolite

Name: Methotrexate metabolite
Brand: Selleck Chemicals
SKU: E7394
Rating: 5 (1 reviews)

Synonyms: DAMPA

Catalog No.E7394 Purity:≥99%

Methotrexate metabolite (DAMPA) is an active metabolite of Methotrexate. Methotrexate is a Folic acid (HY-16637) antagonist, widely used as an immunosuppressant. Methotrexate metabolite is an antimalarial agent that inhibits parasite growth under physiological folic acid conditions, with IC50 values of 446 nM and 812 nM against folic acid-sensitive strains and highly resistant strains, respectively. Methotrexate metabolite exhibits pharmacokinetic characteristics of rapid clearance and extensive metabolism, with a mean clearance rate of 1.9 l/kg/h and a mean terminal half-life of 51 minutes. Methotrexate metabolite is promising for research in the field of inflammation.

Methotrexate metabolite Chemical Structure

CAS No. 19741-14-1

Purity & Quality Control

≥99

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Biological Activity

Description

Chemical Information & Solubility

Molecular Weight	325.33	Formula
CAS No.	19741-14-1	SDF	--
Storage (From the date of receipt)	3 years-20°Cpowder	Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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