Isopropyl myristate

Synonyms: IPM

Isopropyl myristate (IPM) is used as a substitute for natural oils in cosmetics and a co-solvent with skin penetration enhancement properties of active ingredients in many topical and transdermal preparations. It affects the lamellar lipid assembly in terms of bilayer perturbation and disordering.

Isopropyl myristate Chemical Structure

Isopropyl myristate Chemical Structure

CAS No. 110-27-0

Purity & Quality Control

Isopropyl myristate Related Products

Biological Activity

Description Isopropyl myristate (IPM) is used as a substitute for natural oils in cosmetics and a co-solvent with skin penetration enhancement properties of active ingredients in many topical and transdermal preparations. It affects the lamellar lipid assembly in terms of bilayer perturbation and disordering.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05981066 Recruiting
Advanced Hepatocellular Carcinoma
Peking Union Medical College Hospital
July 10 2023 Not Applicable
NCT03319927 Recruiting
Children Only|Risk Reduction|Environmental Exposure
University of California San Francisco|National Institute of Environmental Health Sciences (NIEHS)|University of California Berkeley|Oregon State University
October 9 2017 Not Applicable
NCT02020226 Unknown status
Solid Tumors
Threshold Pharmaceuticals
November 2013 Phase 1
NCT01833546 Completed
Solid Tumor|Pancreatic Cancer
Merck KGaA Darmstadt Germany|Threshold Pharmaceuticals
April 18 2013 Phase 1

Chemical Information & Solubility

Molecular Weight 270.45 Formula

C17H34O2

CAS No. 110-27-0 SDF --
Density 0.85 g/mL at 25 °C
Smiles CCCCCCCCCCCCCC(=O)OC(C)C
Storage (From the date of receipt) 2 years -20°C liquid

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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