Flecainide

Name: Flecainide
Brand: Selleck Chemicals
SKU: E0528
Rating: 5 (1 reviews)

Catalog No.E0528 Purity:99.64%

Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation.

Flecainide Chemical Structure

CAS No. 54143-55-4

Purity & Quality Control

Batch: E052801 DMSO]83 mg/mL]false]Ethanol]21 mg/mL]false]Water]Insoluble]false Purity: 99.64%

99.64

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Biological Activity

Description	Flecainide is a common medication used to help restore and maintain sinus rhythm in patients with atrial fibrillation.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT04991896	Completed	Atrial Fibrillation\|Arrhythmias Cardiac	AHEPA University Hospital\|Skylitseio General Hospital	January 1 2020	--
NCT03685149	Completed	Arrhythmogenic Right Ventricular Cardiomyopathy	Wojciech Zareba\|University of Rochester	July 31 2019	Phase 2
NCT03005366	Completed	Paroxysmal Atrial Fibrillation	David Filgueiras-Rama\|Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III\|Hospital San Carlos Madrid	January 2017	Phase 4
NCT02190175	Completed	Atrial Fibrillation	Hellenic Cardiovascular Research Society	June 2014	--
NCT00945867	Unknown status	Atrial Fibrillation	Assaf-Harofeh Medical Center	September 2009	--

References

[1] Barman M. et al. J Atr Fibrillation. 2015 Dec 31;8(4):1091.

Chemical Information & Solubility

Molecular Weight	414.34	Formula	C₁₇H₂₀F₆N₂O₃
CAS No.	54143-55-4	SDF	--
Smiles	FC(F)(F)COC1=CC=C(OCC(F)(F)F)C(=C1)C(=O)NCC2CCCCN2
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 83 mg/mL ( (200.31 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 21 mg/mL

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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