Home Microbiology Bacterial chemical - Antibiotics chemical Erythromycin Ethylsuccinate For research use only.

Erythromycin Ethylsuccinate

Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.

Erythromycin Ethylsuccinate Chemical Structure

Erythromycin Ethylsuccinate Chemical Structure

CAS No. 1264-62-6

Purity & Quality Control

Erythromycin Ethylsuccinate Related Products

Biological Activity

Description Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
In vitro
In vitro Erythromycin displays antibacterial activity against Staphylococcus aureus, streptococcus pneumonia, Streptococcus pyogenes, Haemophilus influenza, Moraxella catarrhalis, Bordetella pertussis, Neisseria gonorrhoeae, Campylobacter jejuni, Helicobacter pylori, and Borrelia burgdorferi. [1] Erythromycin is a motilin receptor agonist, which is a potent stimulator of gastrointestinal motor activity. The concentrations of Erythromycin required to induce 50% of the maximum contractile response to a supramaximal dose of acetylcholine is 2 μM. The concentrations of Erythromycin required to displace 50% of the labeled motilin is 13 μM. Erythromycin has no effect on muscle strips of rat or dog duodenum but induces contractions in human strips. [2]

Chemical Information & Solubility

Molecular Weight 862.05 Formula

C43H75NO16 
CAS No. 1264-62-6 SDF Download Erythromycin Ethylsuccinate SDF
Smiles CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)OC(=O)CCC(=O)OCC)(C)O)C)C)O)(C)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 172 mg/mL ( (199.52 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 172 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Erythromycin Ethylsuccinate | Erythromycin Ethylsuccinate ic50 | Erythromycin Ethylsuccinate price | Erythromycin Ethylsuccinate cost | Erythromycin Ethylsuccinate solubility dmso | Erythromycin Ethylsuccinate purchase | Erythromycin Ethylsuccinate manufacturer | Erythromycin Ethylsuccinate research buy | Erythromycin Ethylsuccinate order | Erythromycin Ethylsuccinate mouse | Erythromycin Ethylsuccinate chemical structure | Erythromycin Ethylsuccinate mw | Erythromycin Ethylsuccinate molecular weight | Erythromycin Ethylsuccinate datasheet | Erythromycin Ethylsuccinate supplier | Erythromycin Ethylsuccinate in vitro | Erythromycin Ethylsuccinate cell line | Erythromycin Ethylsuccinate concentration | Erythromycin Ethylsuccinate nmr