Dextran

Name: Dextran
Brand: Selleck Chemicals
SKU: S4492
Rating: 5 (1 reviews)

Synonyms: Dextran 40, Macrodex

Catalog No.S4492 Purity:99%

Dextran (Dextran 40, Macrodex) is a kind of biocompatible, nontoxic and nonimmunogenic biological substance that has been widely used in drug-delivery systems.

Dextran Chemical Structure

CAS No. 9004-54-0

Purity & Quality Control

Batch: S449201 DMSO]10 mg/mL]false]Water]10 mg/mL]false]Ethanol]Insoluble]false Purity: 99%

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Biological Activity

Description	Dextran (Dextran 40, Macrodex) is a kind of biocompatible, nontoxic and nonimmunogenic biological substance that has been widely used in drug-delivery systems.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT04700670	Completed	Unfractionated Heparin Treatment	Rennes University Hospital	January 16 2020	--
NCT02691624	Unknown status	Lymphedema of Upper Arm	Peking University People''s Hospital	October 2015	--
NCT05959590	Completed	Osteomyelitis	University of New Mexico	February 12 2014	Phase 1

References

[1] Gangliang Huang, Hualiang Huang. Nanomedicine (Lond). 2018 Dec;13(24):3149-3158.

Chemical Information & Solubility

Molecular Weight		Formula	[C₆H₁₀O₅]_n
CAS No.	9004-54-0	SDF	--
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 10 mg/mL ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 10 mg/mL

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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