Home Biosimilar Antibodies Immunology & Inflammation PD-1/PD-L1 antibody Cosibelimab (Anti-B7-H1 / PD-L1 / CD274) For research use only.
Not for use in humans.

Cosibelimab (Anti-B7-H1 / PD-L1 / CD274)

Synonyms: CK-301; TG-1501

Cosibelimab (Anti-B7-H1 / PD-L1 / CD274) is an immunoglobulin G1 (IgG1), human monoclonal antibody directed against the immunosuppressive ligand programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274), with potential immune checkpoint inhibitory and antineoplastic activities. MW : 144.64 KD.

Cosibelimab (Anti-B7-H1 / PD-L1 / CD274)

Purity & Quality Control

Choose Selective PD-1/PD-L1 Inhibitors

Name Citation PD-1/PD-L1 interaction PD-1 PD-L1 PD-1/PD-L1 Others
GS-4224 0
INCB086550 0
BMS-1001 0
BMS-1166 5
PD-1/PD-L1 Inhibitor 3 12
BMS-1 12
BMS202 21
CA-170 (AUPM-170)
SR 0987 IL17,RORγt
Spartalizumab (anti-PD-1)
Camrelizumab (anti-PD-1)
AUNP-12
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Biological Activity

Description Cosibelimab (Anti-B7-H1 / PD-L1 / CD274) is an immunoglobulin G1 (IgG1), human monoclonal antibody directed against the immunosuppressive ligand programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274), with potential immune checkpoint inhibitory and antineoplastic activities. MW : 144.64 KD.

Product Details

CAS No. 2216751-26-5
Molecular Weight 144.64
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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