Clodronate disodium tetrahydrate

Name: Clodronate disodium tetrahydrate
Brand: Selleck Chemicals
SKU: S5660
Rating: 5 (1 reviews)

Synonyms: clodronic acid disodium tetrahydrate

Catalog No.S5660 Purity:98%

Clodronate disodium tetrahydrate (clodronic acid) is a diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.

Clodronate disodium tetrahydrate Chemical Structure

CAS No. 88416-50-6

Purity & Quality Control

Batch: S566001 Water]72 mg/mL]false]DMSO]Insoluble]false]]]false Purity: 98%

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Biological Activity

Description	Clodronate disodium tetrahydrate (clodronic acid) is a diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.

Chemical Information & Solubility

Molecular Weight	360.92	Formula	CH₁₀Cl₂Na₂O₁₀P₂
CAS No.	88416-50-6	SDF	--
Smiles	C(P(=O)(O)[O-])(P(=O)(O)[O-])(Cl)Cl.O.O.O.O.[Na+].[Na+]
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

Water : 72 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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