Home Microbiology Antineoplastic and Immunosuppressive Antibiotics inhibitor - Bacterial chemical - Antibiotics chemical Cefixime For research use only.

Cefixime

Synonyms: Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635

Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.

Cefixime Chemical Structure

Cefixime Chemical Structure

CAS No. 79350-37-1

Purity & Quality Control

Cefixime Related Products

Biological Activity

Description Cefixime (Cefixima, Cefiximum, Cephoral, Cefspan, FR-17027, FK-027, CL-284635) is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05507736 Recruiting
Pediatric Cancer|Solid Tumor
Fundació Sant Joan de Déu
 January 15 2022 Not Applicable
NCT03752112 Unknown status
Syphilis Female
World Health Organization
 November 22 2019 Phase 1|Phase 2
NCT03969758 Unknown status
Liver Abscess
Post Graduate Institute of Medical Education and Research Chandigarh|PGIMER
 July 2019 Phase 3
NCT03408392 Completed
Infections Bacterial
GlaxoSmithKline
 February 6 2018 Phase 1
NCT03329547 Withdrawn
Infections Bacterial
GlaxoSmithKline
 January 11 2018 Phase 1

Chemical Information & Solubility

Molecular Weight 453.45 Formula

C16H15N5O7S2
CAS No. 79350-37-1 SDF Download Cefixime SDF
Smiles C=CC1=C(N2C(C(C2=O)NC(=O)C(=NOCC(=O)O)C3=CSC(=N3)N)SC1)C(=O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 90 mg/mL ( (198.47 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 1 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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