Home Apoptosis p53 activator C16-Ceramide For research use only.

C16-Ceramide

Synonyms: N-Palmitoylsphingosine

C16-Ceramide is a sphingolipid ligand and an activator of p53 tumor suppressor. It tightly binds within the p53 DNA-binding domain with a Kd of ~ 60 nM, in close vicinity to the Box V motif. It regulates the protein ubiquitination and proteasomal degradation and also induces apoptosis in cancer cells making it a research tool for targeting human cancers.

C16-Ceramide Chemical Structure

C16-Ceramide Chemical Structure

CAS No. 24696-26-2

Purity & Quality Control

Batch: E715401 Ethanol]12 mg/mL]true]DMSO]Insoluble]false]Water]Insoluble]false Purity: ≥98%
≥98

C16-Ceramide Related Products

Signaling Pathway

p53 Signaling Pathways

p53 Signaling Pathway

Biological Activity

Description C16-Ceramide is a sphingolipid ligand and an activator of p53 tumor suppressor. It tightly binds within the p53 DNA-binding domain with a Kd of ~ 60 nM, in close vicinity to the Box V motif. It regulates the protein ubiquitination and proteasomal degradation and also induces apoptosis in cancer cells making it a research tool for targeting human cancers.

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