cis-Bac430

Name: cis-Bac430
Brand: Selleck Chemicals
SKU: E4958
Rating: 5 (1 reviews)

Catalog No.E4958 Purity:98.22%

Cis-Bac430 plays a role in mediating the movement of anti-tumor CD8+cells from the periphery to the tumor site,thus enhancing the anti-tumor effect of an immune checkpoint inhibitor.

cis-Bac430 Chemical Structure

CAS No. 2227449-70-7

Purity & Quality Control

Batch: E495801 DMSO]86 mg/mL]false]Ethanol]86 mg/mL]false]Water]Insoluble]false Purity: 98.22%

98.22

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Biological Activity

Description	Cis-Bac430 plays a role in mediating the movement of anti-tumor CD8+cells from the periphery to the tumor site,thus enhancing the anti-tumor effect of an immune checkpoint inhibitor.

References

[1] Lin H, et al. J Med Chem. 2018 Apr 12;61(7):3224-3230.

Chemical Information & Solubility

Molecular Weight	429.64	Formula	C₂₇H₄₃NO₃
CAS No.	2227449-70-7	SDF	Download cis-Bac430 SDF
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 86 mg/mL ( (200.16 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 86 mg/mL

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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