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Technical Data
| Formula | C21H20N2O3S |
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| Molecular Weight | 380.46 | CAS No. | 557782-81-7 | |
| Solubility (25°C)* | In vitro | DMSO | 76 mg/mL (199.75 mM) | |
| Ethanol | 3 mg/mL (7.88 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | ZINC00881524 is a ROCK inhibitor. |
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Protocol (from reference)
Selleck's ZINC00881524 (ROCK inhibitor) has been cited by 22 publications
| Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes [ bioRxiv, 2023, 2023.06.07.544100] | PubMed: 37333144 |
| A non-coding GWAS variant impacts anthracycline-induced cardiotoxic phenotypes in human iPSC-derived cardiomyocytes [ Nat Commun, 2022, 13(1):7171] | PubMed: 36418322 |
| Development of novel aptamer-based targeted chemotherapy for bladder cancer [ Cancer Res, 2022, canres.2691.2021] | PubMed: 35064018 |
| Telomere shortening impairs alveolar regeneration [ Cell Prolif, 2022, e13211] | PubMed: 35274784 |
| Biphasic cell cycle defect causes impaired neurogenesis in down syndrome [ Front Genet, 2022, 13:1007519] | PubMed: 36313423 |
| Extracellular Matrix in Synthetic Hydrogel-based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 inhibitors [ Adv Mater, 2021, e2100096] | PubMed: 34676924 |
| Bioinspired 3D Culture in Nanoliter Hyaluronic Acid-Rich Core-Shell Hydrogel Microcapsules Isolates Highly Pluripotent Human iPSCs [ Small, 2021, e2102219] | PubMed: 34260817 |
| Upregulation of HOXC9 generates interferon-gamma resistance in gastric cancer by inhibiting the DAPK1/RIG1/STAT1 axis [ Cancer Sci, 2021, 112(9):3455-3468] | PubMed: 34159686 |
| The Role of Small Molecules and Their Effect on the Molecular Mechanisms of Early Retinal Organoid Development [ Int J Mol Sci, 2021, 22(13)7081] | PubMed: 34209272 |
| Single-Cell Atlas Reveals Fatty Acid Metabolites Regulate the Functional Heterogeneity of Mesenchymal Stem Cells [ Front Cell Dev Biol, 2021, 9:653308] | PubMed: 33912565 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.