Xylometazoline HCl

Catalog No.S2576 Batch:S257601

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Technical Data

Formula

C16H24N2.HCl

Molecular Weight 280.84 CAS No. 1218-35-5
Solubility (25°C)* In vitro Water 56 mg/mL (199.4 mM)
Ethanol 56 mg/mL (199.4 mM)
DMSO 27 mg/mL (96.14 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM.
Targets
adrenoceptor α1A [1] adrenoceptor α2C [1] adrenoceptor α1D [1] adrenoceptor α1B [1] adrenoceptor α2A [1] View More
80 nM 220 nM 450 nM 560 nM 980 nM
In vitro Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM. Xylometazoline binds at adrenoceptor subtypeα1A, α1B, α1D, α2A, α2B, α2C with IC50 of 0.08, 0.56, 0.45, 0.98, 1.8, 0.22μM, repectively. [1]

Protocol (from reference)

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.