Uracil

Catalog No.S4177 Batch:S417701

Technical Data

Formula

C₄H₄N₂O₂

Molecular Weight

112.09

CAS No.

66-22-8

Solubility (25°C)*

In vitro

DMSO

22 mg/mL (196.27 mM)

Water

Insoluble

Ethanol

Insoluble

In vivo (Add solvents to the product individually and in order)

Clear solution

5%DMSO 1 Corn oil

2.0mg/ml

Taking the 1 mL working solution as an example, add 50 μL of 40 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description	Uracil is one of the four nucleobases in the nucleic acid of RNA can be used for drug delivery and as a pharmaceutical.
In vitro	Uracil can be used for drug delivery and as a pharmaceutical. It can be reacted with elemental fluorine to produce 5-fluorouracil, which can inhibit RNA replication enzymes, eliminate RNA synthesis and stop the growth of cancerous cells. Uracil can also be used in the synthesis of caffeine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for reactions in the human body and in plants. UMP controls the activity of carbamoyl phosphate synthetase and aspartate transcarbamoylase in plants, while UDP and UTP requlate CPSase II activity in animals. UDP-glucose regulates the conversion of glucose to galactose in the liver and other tissues in the process of carbohydrate metabolism. Uracil is also involved in the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes.

Description

Uracil is one of the four nucleobases in the nucleic acid of RNA can be used for drug delivery and as a pharmaceutical.

In vitro

Uracil can be used for drug delivery and as a pharmaceutical. It can be reacted with elemental fluorine to produce 5-fluorouracil, which can inhibit RNA replication enzymes, eliminate RNA synthesis and stop the growth of cancerous cells. Uracil can also be used in the synthesis of caffeine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for reactions in the human body and in plants. UMP controls the activity of carbamoyl phosphate synthetase and aspartate transcarbamoylase in plants, while UDP and UTP requlate CPSase II activity in animals. UDP-glucose regulates the conversion of glucose to galactose in the liver and other tissues in the process of carbohydrate metabolism. Uracil is also involved in the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes.

Protocol (from reference)

Selleck's Uracil has been cited by 1 publication

A gravity-driven tissue chip to study the efficacy and toxicity of cancer therapeutics [ Lab Chip, 2024, 24(23):5251-5263]	PubMed: 39485368

A gravity-driven tissue chip to study the efficacy and toxicity of cancer therapeutics [ Lab Chip, 2024, 24(23):5251-5263]

PubMed: 39485368

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.