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Formula | C15H22N2O4 |
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Molecular Weight | 294.35 | CAS No. | 30751-05-4 | |
Solubility (25°C)* | In vitro | DMSO | 18 mg/mL (61.15 mM) | |
Ethanol | 3 mg/mL (10.19 mM) | |||
Water | Insoluble | |||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
Description | Troxipide(KU 54) is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum. |
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In vitro | Troxipide is a novel antiulcer compound which has inhibitory effects on human neutrophil migration and activation induced by various stimulants.[1] Troxipide is a new gastric cytoprotective agent, which neither inhibits acid secretion nor has acid neutralizing activity, but has been clinically proven to heal gastritis and gastric ulcers. Troxipide is shown to inhibit neutrophil mediated inflammation and oxidative stress in addition to improving the gastric mucus composition and output. Furthermore, it is found to increase the secretion of cytoprotective prostaglandins. The gastric mucosal metabolism and blood flow are also enhanced by Troxipide. [2] |
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3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma [ J Clin Invest, 2022, 132(24)e151604] | PubMed: 36282600 |
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