Trazodone

Catalog No.S5857 Batch:S585701

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Technical Data

Formula

C19H22ClN5O

Molecular Weight 371.86 CAS No. 19794-93-5
Solubility (25°C)* In vitro DMSO 45 mg/mL (121.01 mM)
Ethanol 17 mg/mL (45.71 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders.
Targets
5-HT2A [1] 5-HT2C [1]

Protocol (from reference)

Selleck's Trazodone has been cited by 4 publications

Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis [ Biomolecules, 2023, 10.3390/biom13091321] PubMed: 37759721
Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis [ Biomolecules, 2023, 13(9)1321] PubMed: 37759721
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain [ J Lipid Res, 2022, 63(8):100249] PubMed: 35839864
Effects of Psychotropic Medication on Somatic Sterol Biosynthesis of Adult Mice [ Biomolecules, 2022, 12(10)1535] PubMed: 36291744

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.