(±)-α-Tocopherol

Catalog No.S6104 Batch:S610401

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Technical Data

Formula

C29H50O2
Molecular Weight 430.71 CAS No. 10191-41-0
Solubility (25°C)* In vitro Ethanol 100 mg/mL (232.17 mM)
DMSO (warmed with 50ºC water bath) 16 mg/mL (37.14 mM)
Water Insoluble
In vivo (Add solvents to the product individually and in order)
Clear solution
5%DMSO 40%PEG300 5%Tween80 50%ddH2O
0.8mg/ml Taking the 1 mL working solution as an example, add 50 μL of 16 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results. 
Clear solution
5% DMSO 95% Corn oil
0.8mg/ml Taking the 1 mL working solution as an example, add 50 μL of 16 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results. 
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description (±)-α-Tocopherol is a biologically active form of vitamin E, which is a lipid-soluble antioxidant that protects cellular membranes from oxidative damage.
Density 0.950 g/mL at 20 °C

Protocol (from reference)

Selleck's (±)-α-Tocopherol has been cited by 8 publications

Targeting N-glycosylation of 4F2hc mediated by glycosyltransferase B3GNT3 sensitizes ferroptosis of pancreatic ductal adenocarcinoma [ Cell Death Differ, 2023, 30(8):1988-2004] PubMed: 37479744
Silibinin Inhibits Cell Ferroptosis and Ferroptosis-Related Tissue Injuries [ Antioxidants (Basel), 2023, 12(12)2119] PubMed: 38136238
α-tocopherol pretreatment alleviates cerebral ischemia-reperfusion injury in rats [ CNS Neurosci Ther, 2022, 28(6):964-970] PubMed: 35301808
Effect of α-tocopherol in alleviating the lipopolysaccharide-induced acute lung injury via inhibiting nuclear factor kappa-B signaling pathways [ Bioengineered, 2022, 13(2):3958-3968] PubMed: 35112986
HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes [ J Mol Cell Cardiol, 2021, 150:65-76] PubMed: 33098823
HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes [ J Mol Cell Cardiol, 2021, 150:65-76] PubMed: 33098823
Tailored theranostic nanoparticles cause efficient ferroptosis in head and neck squamous cell carcinoma through a reactive oxygen species “butterfly effect” [ CHEM ENG J, 2021, 10.1016/j.cej.2021.130083] PubMed: None
Luteolin selectively kills STAT3 highly activated gastric cancer cells through enhancing the binding of STAT3 to SHP-1. [ Cell Death Dis, 2017, 8(2):e2612] PubMed: 28182003

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.