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Technical Data
| Formula | C9H8ClN5S |
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| Molecular Weight | 253.71 | CAS No. | 51322-75-9 | |
| Solubility (25°C)* | In vitro | DMSO | 50 mg/mL (197.07 mM) | |
| Water | 15 mg/mL (59.12 mM) | |||
| Ethanol | 6 mg/mL (23.64 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Tizanidine is an imidazoline derivative and a centrally acting α2 adrenergic agonist used as a muscle relaxant for therapy of acute muscle spasms and chronic spasticity. | |
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| In vitro | Like clonidine, it has sedative, anxiolytic, and analgesic properties, but it has a shorter duration of action and less effect on heart rate and blood pressure[1]. | |
| In vivo | Tizanidine is shown to significantly reduce pain and tissue tenderness and to improve the quality of sleep[1]. |
Protocol (from reference)
Selleck's Tizanidine has been cited by 1 publication
| Characterization of a Novel CYP1A2 Knockout Rat Model Constructed by CRISPR/Cas9 [ Drug Metab Dispos, 2021, 49(8):638-647] | PubMed: 34074728 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.