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Technical Data
| Formula | C6H12N3PS |
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| Molecular Weight | 189.22 | CAS No. | 52-24-4 | |
| Solubility (25°C)* | In vitro | DMSO | 38 mg/mL (200.82 mM) | |
| Water | 38 mg/mL (200.82 mM) | |||
| Ethanol | 38 mg/mL (200.82 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Thiotepa (Thioplex, Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide) is an alkylating agent used to treat cancer. |
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Protocol (from reference)
Selleck's Thiotepa has been cited by 5 publications
| ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells [ Oncotarget, 2024, 15:220-231] | PubMed: 38484153 |
| Patient- and xenograft-derived organoids recapitulate pediatric brain tumor features and patient treatments [ EMBO Mol Med, 2023, 15(12):e18199] | PubMed: 38037472 |
| Tepotinib suppresses proliferation, invasion, migration, and promotes apoptosis of melanoma cells via inhibiting MET and PI3K/AKT signaling pathways [ Oncol Lett, 2022, 23(6):170] | PubMed: 35497936 |
| High replication stress and limited Rad51-mediated DNA repair capacity, but not oxidative stress, underlie oligodendrocyte precursor cell radiosensitivity [ NAR Cancer, 2022, 4(2):zcac012] | PubMed: 35425901 |
| TRPS1 drives heterochromatic origin refiring and cancer genome evolution [ Cell Rep, 2021, 34(10):108814] | PubMed: 33691114 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.