|
Toll Free: (877) 796-6397 -- USA and Canada only -- |
Fax: +1-832-582-8590 Orders: +1-832-582-8158 |
Tech Support: +1-832-582-8158 Ext:3 Please provide your Order Number in the email. |
Technical Data
| Formula | C54H83NaO23 |
|||
| Molecular Weight | 1123.21 | CAS No. | 20977-05-3 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (89.03 mM) | |
| Water | 100 mg/mL (89.03 mM) | |||
| Ethanol | Insoluble | |||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
||||
Preparing Stock Solutions
Biological Activity
| Description | Sodium Aescinate (SA, Escin Sodium Salt) is a widely-applied triterpene saponin product derived from horse chestnut seeds, possessing vasoactive and organ-protective activities with oral or injection administration in the clinic. Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway. | |
|---|---|---|
| Targets |
|
|
| In vivo | Sodium aescinate (SA) prevents and alleviates acute lung injury induced by oleic acid[1]. It is used as a vasoactive drug in clinical treatment. Topical application of SA can accelerate wound healing significantly marked by compact collagen deposition and newly regenerated epithelial layer. Sodium aescinate (SA) may effectively control and improve wound healing in diabetic rats via its anti-inflammatory and antioxidant activities[2]. |
Protocol (from reference)
| Animal Study: |
|
|---|
References
|
Selleck's Sodium Aescinate has been cited by 2 publications
| Sodium aescinate alleviates neuropathic pain through suppressing OGT-mediated O-GlcNAc modification of TLR3 to inactivate MAPK signaling pathway [ Brain Res Bull, 2024, 217:111077] | PubMed: 39265741 |
| Sodium aescinate inhibits microglia activation through NF-κB pathway and exerts neuroprotective effect [ Front Pharmacol, 2023, 14:1086429] | PubMed: 36778008 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.