|
Toll Free: (877) 796-6397 -- USA and Canada only -- |
Fax: +1-832-582-8590 Orders: +1-832-582-8158 |
Tech Support: +1-832-582-8158 Ext:3 Please provide your Order Number in the email. |
Technical Data
| Formula | C129H230N36O29S
|
|||
| Molecular Weight | 2781.50 | CAS No. | 213546-53-3 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (35.95 mM) | |
| Water | 100 mg/mL (35.95 mM) | |||
| Ethanol | 100 mg/mL (35.95 mM) | |||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
||||
Preparing Stock Solutions
Biological Activity
| Description | SN50 (NF-κB SN50), a cell-permeable NF-κB inhibitory peptide, is composed of the signal peptide of Kaposi fibroblast growth factor.SN50 inhibits the activation of NF-κB and attenuates ventilator-induced lung injury. | |
|---|---|---|
| Targets |
|
Protocol (from reference)
Selleck's SN50 has been cited by 4 publications
| DJ-1 inhibits microglial activation and protects dopaminergic neurons in vitro and in vivo through interacting with microglial p65 [ Cell Death Dis, 2021, 12(8):715] | PubMed: 34274951 |
| Integrin αv and Vitronectin Prime Macrophage-Related Inflammation and Contribute the Development of Dry Eye Disease [ Int J Mol Sci, 2021, 22(16)8410] | PubMed: 34445121 |
| miR-182 mediated the inhibitory effects of NF-κB on the GPR39/CREB/BDNF pathway in the hippocampus of mice with depressive-like behaviors [ Behav Brain Res, 2021, 418:113647] | PubMed: 34743948 |
| Anti-aging effects of Schisandrin C on H2O2-induced HaCaT [ Med J Chin PLA, 2021, Vol. 46, Iss. 3, (2021): 221-230] | PubMed: N/A |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.