SMI-16a

Catalog No.S6497 Batch:S649701

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Technical Data

Formula

C13H13NO3S

Molecular Weight 263.31 CAS No. 587852-28-6
Solubility (25°C)* In vitro DMSO 53 mg/mL (201.28 mM)
Ethanol 4 mg/mL (15.19 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description SMI-16a is a selective Pim kinase inhibitor with IC50 values of 150 nM and 20 nM for Pim1 and Pim2 respectively.
Targets
Pim2 [1] Pim1 [1]
20 nM 150 nM

Protocol (from reference)

Selleck's SMI-16a has been cited by 1 publication

Pim-2 regulates bone resorptive activity of osteoclasts via V-ATPase a3 isoform expression in periodontal disease [ J Cell Physiol, 2022, 10.1002/jcp.30814] PubMed: 35696529

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.