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Technical Data
| Formula | C32H46O16 |
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| Molecular Weight | 686.7 | CAS No. | 148244-82-0 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (145.62 mM) | |
| Water | 100 mg/mL (145.62 mM) | |||
| Ethanol | 100 mg/mL (145.62 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Secoisolariciresinol diglucoside (SDG), a plant lignan isolated from flaxseed, has strong antioxidant activity, cardioprotective effects, reduces the blood levels of low-density lipoprotein cholesterol, and reduces the risk of hormone related cancer. |
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| In vitro | Secoisolariciresinol diglucoside (SDG) inhibits colon cancer cell growth by inducing S-phase cell cycle arrest[1]. SDG is effective in mitigating iron-induced cellular damage and death. SDG is capable of preventing the increase in inflammation in iron treated cells[2]. |
| In vivo | Secoisolariciresinol diglucoside (SDG) has been shown to decrease the production of inflammatory mediators and reduce oxidative stress. Its treatment is also found to reduce the development of hypercholesterolemic atherosclerosis in rabbits fed a high cholesterol diet, and reduce the development of diabetes in rats. SDG prevents the development of hypercholesterolemic atherosclerosis, induces angiogenesis-mediated cardioprotection, and prevents the development of type 1 and type 2 diabetes. SDG may have a cardioprotective role in cardiac iron overload[2]. |
Protocol (from reference)
References
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RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.