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Technical Data
| Formula | C42H70-nO35.nNa.n(C4H8O3S) |
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| Molecular Weight | CAS No. | 182410-00-0 | ||
| Solubility (25°C)* | In vitro | Water | 100 mg/mL | |
| DMSO | Insoluble | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | SBE-β-CD is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs. |
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Protocol (from reference)
Selleck's SBE-β-CD has been cited by 25 publications
| An experimentally validated approach to automated biological evidence generation in drug discovery using knowledge graphs [ Nat Commun, 2024, 15(1):5703] | PubMed: 38977662 |
| EGFR inhibits TNF-α-mediated pathway by phosphorylating TNFR1 at tyrosine 360 and 401 [ Cell Death Differ, 2024, 10.1038/s41418-024-01316-3] | PubMed: 38789573 |
| PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity [ Nat Commun, 2023, 14(1):2806] | PubMed: 37193698 |
| Harnessing PROTAC technology to combat stress hormone receptor activation [ Nat Commun, 2023, 14(1):8177] | PubMed: 38071198 |
| Secreted phospholipase A2 modifies extracellular vesicles and accelerates B cell lymphoma [ Cell Metab, 2022, S1550-4131(22)00083-3] | PubMed: 35294862 |
| FGF1 and insulin control lipolysis by convergent pathways [ Cell Metab, 2022, 34(1):171-183.e6] | PubMed: 34986332 |
| TNK2/ACK1-mediated phosphorylation of ATP5F1A (ATP synthase F1 subunit alpha) selectively augments survival of prostate cancer while engendering mitochondrial vulnerability [ Autophagy, 2022, 1-26] | PubMed: 35895804 |
| The KRAS-G12D mutation induces metabolic vulnerability in B-cell acute lymphoblastic leukemia [ iScience, 2022, 25(3):103881] | PubMed: 35243242 |
| Data-Driven Identification of Biomarkers for In Situ Monitoring of Drug Treatment in Bladder Cancer Organoids [ Int J Mol Sci, 2022, 23(13)6956] | PubMed: 35805961 |
| The transglutaminase 2 cancer cell survival factor maintains mTOR activity to drive an aggressive cancer phenotype [ Mol Carcinog, 2022, 10.1002/mc.23446] | PubMed: 35848131 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.