Sabatolimab (anti-TIM-3)

Catalog No.A2037 Batch: A203704

Technical Data

CAS No.	2252262-24-9
Formulation	PBS Buffer, PH 7.4
Isotype	Human IgG4, κ
Application	Sabatolimab (anti-TIM-3)
Source	CHO cells
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
Purity	99.34%
Protein concentration	3mg/ml
Endotoxin Level	< 2EU/mg

Biological Activity

Description	Sabatolimab (anti-TIM-3) (MBG453, NVP-MBG453) is a high-affinity, humanized IgG4 antibody targeting TIM-3 on the surface of T-cells.

References	[1] Andrew M. Brunner, MD, et al. Blood (2020) 136 (Supplement 1): 1–2.

References

[1] Andrew M. Brunner, MD, et al. Blood (2020) 136 (Supplement 1): 1–2.

Customer Product Validation

Selleck's Sabatolimab (anti-TIM-3) has been cited by 2 publications

Human papillomavirus-encoded circular RNA circE7 promotes immune evasion in head and neck squamous cell carcinoma [ Nat Commun, 2024, 15(1):8609]	PubMed: 39366979
Single-cell analysis of the survival mechanisms of fratricidal CAR-T targeting of T cell malignancies [ Mol Ther Nucleic Acids, 2024, 35(2):102225]	PubMed: 38948332

FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS.

Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products are stable under the recommended conditions. Products are sometimes shipped at a temperature that differs from the recommended storage temperature. Short-term storage of many products are stable in the short-term at temperatures that differ from that required for long-term storage.
We ensure that the product is shipped under conditions that will maintain the quality of the reagents. Upon receipt of the product, follow the storage recommendations on the product data sheet.