S-Gboxin

Catalog No.S0096 Batch:S009601

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Technical Data

Formula

C27H32F3IN2O2

Molecular Weight 600.45 CAS No. 2101317-21-7
Solubility (25°C)* In vitro DMSO 100 mg/mL (166.54 mM)
Ethanol 100 mg/mL (166.54 mM)
Water ˂1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description S-Gboxin, a functional analogue of Gboxin, is an oxidative phosphorylation (OXPHOS) inhibitor which inhibits growth of mouse and human glioblastoma (GBM) with IC50 of 470 nM.
Targets
OXPHOS [1] GBM [1]
(Cell-based assay)
470 nM

Protocol (from reference)

Selleck's S-Gboxin has been cited by 2 publications

Clinical-proteomic classification and precision treatment strategy of chordoma [ Cell Rep Med, 2024, 5(10):101757] PubMed: 39368483
Disrupting metformin adaptation of liver cancer cells by targeting the TOMM34/ATP5B axis [ EMBO Mol Med, 2022, 14(12):e16082] PubMed: 36321555

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.