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Technical Data
| Formula | C15H20Cl2N2O3 |
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| Molecular Weight | 347.24 | CAS No. | 84225-95-6 | |
| Solubility (25°C)* | In vitro | DMSO | 69 mg/mL (198.7 mM) | |
| Ethanol | 69 mg/mL (198.7 mM) | |||
| Water | 1 mg/mL (2.87 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | Raclopride is a selective dopamine D2/D3 receptor antagonist that discriminates between dopamine-mediated motor functions. Raclopride binds to D2 and D3 receptors with dissociation constants of between 1.8 nM and 3.5 nM, but has a very low affinity for D4 receptors. | ||||
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| In vivo | Raclopride is an antagonist of central dopaminergic D2 receptors, possessing antiaggressive effect of raclopride with very little motor impairment and some increase in exploratory behavior.[2] |
Protocol (from reference)
| Animal Study: |
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References
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
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