Polybrene (Hexadimethrine Bromide)

Catalog No.E1299 Batch:E129902

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Technical Data

Formula

(C13H30N2)n.2Br

Molecular Weight 1122.6 CAS No. 28728-55-4
Solubility (25°C)* In vitro Water 100 mg/mL (89.07 mM)
DMSO Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description Polybrene (Hexadimethrine bromide) is a cationic polymer which is widely used as supplement for retroviral and lentiviral transduction.

Protocol (from reference)

Selleck's Polybrene (Hexadimethrine Bromide) has been cited by 5 publications

Wild-type IDH2 is a therapeutic target for triple-negative breast cancer [ Nat Commun, 2024, 15(1):3445] PubMed: 38658533
Palmitoylation of NLRP3 Modulates Inflammasome Activation and Inflammatory Bowel Disease Development [ J Immunol, 2024, ji2300241] PubMed: 38949555
UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway [ Drug Des Devel Ther, 2023, 17:1357-1369] PubMed: 37181827
UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway [ Drug Des Devel Ther, 2023, 17:1357-1369] PubMed: 37181827
Check for updates Chapter 24 [ Computational Vaccine Design, 2023, 10.1007/978-1-0716-3239-0] PubMed: none

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.