PKI 14-22 amide,myristoylated

Catalog No.P1154 Batch:P115401

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Technical Data

Formula

C53H100N20O12

Molecular Weight 1209.49 CAS No. 201422-03-9
Solubility (25°C)* In vitro DMSO 100 mg/mL (82.67 mM)
Water 3 mg/mL (2.48 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

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Biological Activity

Description PKI 14-22 amide, myristoylated is a potent cAMP-dependent PKA inhibitor, which can reduce the IgG-mediated phagocytic response and also inhibits neutrophil adhesion.
Targets
PKA [1]
Density 95.0~105.0%

Protocol (from reference)

Selleck's PKI 14-22 amide,myristoylated has been cited by 1 publication

Paradoxical Induction of ALOX15/15B by Cortisol in Human Amnion Fibroblasts: Implications for Inflammatory Responses of the Fetal Membranes at Parturition [ Int J Mol Sci, 2023, 24(13)10881] PubMed: 37446059

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.