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Technical Data
| Formula | C6H6N2O |
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| Molecular Weight | 122.12 | CAS No. | 1452-77-3 | |
| Solubility (25°C)* | In vitro | DMSO | 24 mg/mL (196.52 mM) | |
| Water | 24 mg/mL (196.52 mM) | |||
| Ethanol | 24 mg/mL (196.52 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | Picolinamide (2-Pyridinecarboxamide, Picolinoylamide, 2-Carbamoylpyridine) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells. | ||
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| Targets |
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| In vivo | Overnight treatment of rats with picolinamide, administered as a single injection (4 mmol/kg), inhibits Na+/phosphate cotransport by isolated renal brush border membrane vesicles. There is only a small increase (1.5-fold) in renal cortical NAD content after picolinamide treatment[3]. |
Protocol (from reference)
| Animal Study:[1] |
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References
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Selleck's Picolinamide has been cited by 2 publications
| Substance P promotes epidural fibrosis via induction of type 2 macrophages [ Neural Regen Res, 2023, 18(10):2252-2259] | PubMed: 37056145 |
| Substance P promotes epidural fibrosis via induction of type 2 macrophages [ Neural Regen Res, 2023, 18(10):2252-2259] | PubMed: 37056145 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.