PF-07220060 (CDK4/6-IN-6)

Catalog No.E1495 Batch:E149502

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Technical Data

Formula

C22H27ClFN5O3

Molecular Weight 463.93 CAS No. 2380321-51-5
Solubility (25°C)* In vitro DMSO 93 mg/mL (200.46 mM)
Ethanol 93 mg/mL (200.46 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description PF-07220060 (CDK4/6-IN-6) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively.
Targets
CDK4/CyclinD1 [1] CDK6/cyclin D3 [1]
0.6 nM(Ki) 13.9 nM(Ki)

Protocol (from reference)

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.