Tagtociclib (PF-07104091)

Catalog No.S9878 Batch:S987803

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Technical Data

Formula

C19H28N6O4

Molecular Weight 404.46 CAS No. 2460249-19-6
Solubility (25°C)* In vitro DMSO 81 mg/mL (200.26 mM)
Ethanol 40 mg/mL (98.89 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Tagtociclib (PF-07104091) inhibits CDK2, which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.
Targets
CDK2 [1]

Protocol (from reference)

Selleck's Tagtociclib (PF-07104091) has been cited by 1 publication

Uncoupling of mTORC1 from E2F activity maintains DNA damage and senescence [ Nat Commun, 2024, 15(1):9181] PubMed: 39448567

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.