PF-06282999

Catalog No.S6648 Batch:S664801

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Technical Data

Formula

C13H12ClN3O3S

Molecular Weight 325.77 CAS No. 1435467-37-0
Solubility (25°C)* In vitro DMSO 65 mg/mL (199.52 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description PF-06282999 is an orally bioavailable, irreversible inactivator of myeloperoxidase enzyme and is currently in clinical trials for the potential treatment of cardiovascular diseases.
Targets
MPO [1]
(LPS-stimulated human whole blood)
1.9 μM

Protocol (from reference)

Selleck's PF-06282999 has been cited by 1 publication

Comparison of quantification of selenocyanate and thiocyanate in cultured mammalian cells between HPLC-fluorescence detector and HPLC-inductively coupled plasma mass spectrometer [ J Chromatogr B Analyt Technol Biomed Life Sci, 2021, 1181:122924] PubMed: 34508979

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.