|
Toll Free: (877) 796-6397 -- USA and Canada only -- |
Fax: +1-832-582-8590 Orders: +1-832-582-8158 |
Tech Support: +1-832-582-8158 Ext:3 Please provide your Order Number in the email. |
Technical Data
| Formula | C56H70N9NaO23S |
|||
| Molecular Weight | 1292.26 | CAS No. | 208538-73-2 | |
| Solubility (25°C)* | In vitro | DMSO | 100 mg/mL (77.38 mM) | |
| Water | 100 mg/mL (77.38 mM) | |||
| Ethanol | Insoluble | |||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
||||
Preparing Stock Solutions
Biological Activity
| Description | Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug. |
|---|---|
| In vitro | Micafungin is an antifungal agent that does not inhibit bacteria. Although micafungin does not inhibit the bacteria directly, it does promote the survival of G. mellonella[1]. Micafungin inhibits biofilm formation by impeding 1,3-β-D-glucan synthesis in Candida albicans[2]. |
Protocol (from reference)
| Cell Assay: |
|
|---|---|
| Animal Study: |
|
References
|
Customer Product Validation
-
Data from [Data independently produced by , , Cell Physiol Biochem, 2016, 584-95]
-
Data from [Data independently produced by , , Virol J, 2016, 13(1):99.]
-
Data from [Data independently produced by , , Antiviral Res, 2018, 159:134-142]
Selleck's Micafungin Sodium has been cited by 13 publications
| Upc2-mediated mechanisms of azole resistance in Candida auris [ Microbiol Spectr, 2024, e0352623.] | PubMed: 38206035 |
| Antiviral activity and mechanism of the antifungal drug, anidulafungin, suggesting its potential to promote treatment of viral diseases [ BMC Med, 2022, 20(1):359] | PubMed: 36266654 |
| Synergistic in-vitro antiviral effects of combination treatment using anidulafungin and T-1105 against Zika virus infection [ Antiviral Res, 2021, S0166-3542(21)00178-9] | PubMed: 34648875 |
| Micafungin Inhibits Dengue Virus Infection through the Disruption of Virus Binding, Entry, and Stability [ Pharmaceuticals (Basel), 2021, 14(4)338] | PubMed: 33917182 |
| Assessment of the In Vitro and In Vivo Antifungal Activity of NSC319726 against Candida auris [ Microbiol Spectr, 2021, 9(3):e0139521] | PubMed: 34730380 |
| Evaluation of artemisinin derivative artemether as a fluconazole potentiator through inhibition of Pdr5 [ Bioorg Med Chem, 2021, 44:116293] | PubMed: 34243044 |
| Inhibiting Fungal Echinocandin Resistance by Small-Molecule Disruption of Geranylgeranyltransferase Type I Activity. [ Antimicrob Agents Chemother, 2020, 64(2)] | PubMed: 31791942 |
| Molecular Identification and Antifungal Susceptibility Profile of Yeast From Vulvovaginal Candidiasis [ BMC Infect Dis, 2020, 19;20(1):287] | PubMed: 32393342 |
| The fungal cell wall as a target for the development of new antifungal therapies. [ Biotechnol Adv, 2019, 37(6):107352] | PubMed: 30797093 |
| Micafungin is a novel anti-viral agent of chikungunya virus through multiple mechanisms [Ho YJ, et al. Antiviral Res, 2018, 159:134-142] | PubMed: 30300716 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.