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Technical Data
| Formula | C7H8O2 |
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| Molecular Weight | 124.14 | CAS No. | 150-76-5 | |
| Solubility (25°C)* | In vitro | DMSO | 25 mg/mL (201.38 mM) | |
| Water | 25 mg/mL (201.38 mM) | |||
| Ethanol | 25 mg/mL (201.38 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Mequinol (4-Methoxyphenol) is a depigmentation agent. |
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| In vitro | Mequinol, diluted in the culture medium or used topically at the top of the RE, leads to a decrease in pigmentation with a diminished melanin transfer human keratinocytes and melanocytes. Mequinol induces a diminution of dopa-positive melanocyte counts. [1] Mequinol is available in the United States in 2% concentration and is commercially marketed as a prescription skin lightener in combination with 0.01% tretinoin, functioning as a penetration enhancer, and vitamin C, in the form of ascorbic acid and ascorbyl palmitate, to enhance skin lightening. Mequinol is a substrate for tyrosinase thereby acting as a competitive inhibitor in the formation of melanin precursors. [2] |
Protocol (from reference)
References
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
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